SYNTHESIS OF N-BENZYLPIPERIDINE-4-ON DERIVATIVES (Review)

Authors

  • Altynay Kaldybayeva A.B. Bekturov Institute of Chemical Sciences JSC
  • Aida Sergazy Al-Farabi Kazakh National University
  • Aigul Malmakova A.B. Bekturov Institute of Chemical Sciences JSC
  • Valentina Yu A.B. Bekturov Institute of Chemical Sciences JSC

DOI:

https://doi.org/10.51580/2024-3.2710-1185.33

Keywords:

N-benzylpiperidin-4-one derivatives, synthesis, structure, biologically active drugs, building block.

Abstract

Introduction: In the field of organic synthetic pharmaceuticals, methods for the
discovery, creation, and synthesis of universal molecules with pharmacological activity are rapidly
advancing worldwide. Optimal synthesis methods enable the production of analytically pure biologically
active compounds with the highest possible yields and minimal waste, which helps conserve resources,
time, and money. The diversity of biologically active drug groups increases the ability to meet the medical
needs of the population. The search for optimal synthesis methods drives the development of new
technologies and techniques, which, in turn, contributes to scientific discoveries in the fields of Medicine
and Chemistry. The purpose of this review is to examine the literature on methods for obtaining
biologically active derivatives of N-benzylpiperidin-4-one published in scientific journals. Research
Object: Derivatives of N-benzylpiperidin-4-one. Research results: The study of the reactivity of Nbenzylpiperidin-4-one derivatives confirms their versatility in various chemical reactions, highlighting
their utility as chemical compounds. The results compiled in scientific literature demonstrate the potential
of N-benzylpiperidin-4-one derivatives in the development of new drugs with various pharmacological
properties. Conclusion: The properties of the N-benzylpiperidin-4-one molecule as a universal chemical
building block indicate its wide application in medicine and pharmacology, enhancing its significance in
further scientific research and the synthesis of new compounds.

Author Biographies

Altynay Kaldybayeva, A.B. Bekturov Institute of Chemical Sciences JSC

PhD, Scientific researcher

Aida Sergazy, Al-Farabi Kazakh National University

Engineer, master student

Aigul Malmakova, A.B. Bekturov Institute of Chemical Sciences JSC

PhD, Leading researcher

Valentina Yu , A.B. Bekturov Institute of Chemical Sciences JSC

Head of the laboratory, Doctor of Chemical Sciences

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Published

2024-09-30