SYNTHESIS OF IONIC COMPOUNDS BASED ON TRIMECAINE IN CLASSICAL CONDITION AND USING ALTERNATIVE METHODS

Abstract

This article presents the results of the synthesis of new and known ionic compounds based on 2-diethylamino-N-(2,4,6-trimethylphenyl)acetamide (trimecaine) in the classical conditions and using microwave and ultrasound activation. Syntheses of ionic compounds were performedviaN-alkylation of trimecaine with iodoalkanes. The highest yields were observed when microwave irradiation was used to promote the reaction, ultrasound activation was less effective and mild yields were observed in classical conditions.

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