ANALYSIS OF CYTOTOXIC ACTIVITY AND QUANTITY OF BIOLOGICALLY ACTIVE METALS OF THE AERIAL MASS OF TAMARIX HISPIDA

Abstract

This article considers the quantitative content of bioactive metals, and the cytotoxic activity of the aboveground mass of the plant Tamarixhispida of the family Tamaricaceae harvested in September 2016 in the Almaty region. Determination of the number of metals was carried out by atomic absorption spectroscopy, and cytotoxic activity using the larvae of Artemiasalina shrimps in concentrations of 10, 100 and 1000 μl in aqueous medium by the LD 50 method, that is, determination of the concentration level of the substance in which more than 50 subjects do not survive organisms. As a result, we found out that the content of biometals in the above-ground mass of Tamarixhispida does not exceed the parameters specified in the State Pharmacopoeia as permissible, and the cytotoxic activity of 50% ethanol, 70% ethanol, ethyl acetate, hexane and dichloromethane extract is practically absent, while 90 % the extract showed a relatively high level of cytotoxic activity.

References

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