SYNTHESIS AND STRUCTURE OF 1,5-BIS(AMINOBUTYNILOXY)NAPHTHALINES
Keywords:
Mannich reaction, 1,5-di(prop-2-ynyloxy)naphthalene, aminomethylation, 1,5-bis(aminobutynyloxy)naphthalenes, 1H and 13C NMR, PASS predictionAbstract
New potentially biologically active 1,5-bis(aminobutynyloxy)naphthalenes were synthesized by the interaction of dipropynyloxynaphthalene with paraform and secondary amines under the catalysis of CuJ in dry dioxane at 45 °C.
References
[1] Chukhadzhyan E.O., Gevorkyan A.R., Chukhadzhyan El.O., Shakhatuni K.G. Sintez dialkil (4-gidroksi-2-butinil) aminov // ZH. Org. Khim. 2000. Vol. 36, vyp. 9. P. 1304-1305.
[2] Dubrovina K.A., Kurmankulov N.B., Yerzhanov K.B., Butin B.M., Praliyev S.Zh. Udobnyy preparativnyy sintez 3-zameshchennykh 2,6-diarilpperidin-4-onov // Aktual'nyye problemy nauki i obrazovaniya v oblasti khimii i biologii. Almaty, 2005. P. 340-341.
[3] Sycheva Ye.S., Asylkhanov ZH.S., Saktaganov A.Ye., Kurmankulov N.B., Yerzhanov K.B. Sintez i khimicheskiye modifikatsii 1,5-di (prop-2-iniloksi) naftalina // Mater. mezhdunar. konf. Novini za moderna nauka. Bolgariya, 2010. P. 11-14.
[4] Sycheva Ye.S., Anuarbekova I.N., Asylkhanov ZH.S., Yerzhanov K.B., Seylkhanov T.M. Sintez novykh aminovykh proizvodnykh na osnove 1,5-di (prop-2-iniloksi) naftalina // Mater. Mezhdunar. konf. «Tendentsii razvitiya nauki i obrazovaniya v oblasti yestestvennonauchnykh distsiplin». Almaty, 2016. P. 157-159.
[5] Poroykov V.V., Filimonov D.A., Gloriozova T.A., Lagunin A.A., Druzhilovskiy D.S., Stepanchikova A.V. Komp'yuternoye predskazaniye biologicheskoy aktivnosti khimicheskikh veshchestv: virtual'naya khemogenomika // Vavilovskiy zhurnal genetiki i selektsii. 2009. Vol. 13, N 1. P. 137-143.
