SUPRAMOLECULAR COMPLEX OF 1-METHYL-4- (3-(NAFTYL-1-OXY) PROP-1-INYL)PIPERIDIN-4-OL WITH SULPHATED ARABINOGALACTAN

Authors

  • Ye. S. SYCHEVA A.B. Bekturov Institute of chemical sciences
  • I. N. ANUARBEKOVA A.B. Bekturov Institute of chemical sciences
  • M. S. MUKANOVA A.B. Bekturov Institute of chemical sciences
  • Т. М. SEILKHANOV Sh. Ualikhanov Kokshetau State University

Keywords:

1-Methyl-4-(3-(naphthyloxy)prop-1-ynyl)piperidin-4-ol, sulfated arabi-nogalactan, supramolecular inclusion complex, NMR 1H and 13С spectroscopy

Abstract

A synthesis of the supramolecular inclusion complex of 1-methyl-4-(3-(naphthyl-1-hydroxy)prop-1-ynyl)piperidin-4-ol with sulfated arabinogalactan was deve-loped. The optimal conditions for the interaction of the preparation KN-2 with AG-SO3H were developed, choosing the mass ratios of the starting reagents, solvents and the duration of the reaction. For many years at A.B. Bekturov Institute of Chemical Sciences the fundamental and applied research on creation of new highly effective and environmentally safe plant growth regulators have been carried out. The structure of the supramolecular inclusion complex of 1-methyl-4-(3-(naphthyl-1-hydroxy)prop-1-ynyl)piperidin-4-ol with sulfated arabinogalactan was studied by the methods of 1H and 13C NMR. The synthesized new supramolecular complex promising as a preparation with low toxi-city, biodegradability and high bioavailability for use in the pharmaceutical and agricul-tural practice.

References

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Published

2021-05-03